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mmp 1  (Cusabio)


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    Structured Review

    Cusabio mmp 1
    Mmp 1, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 51 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mmp 1/product/Cusabio
    Average 93 stars, based on 51 article reviews
    mmp 1 - by Bioz Stars, 2026-02
    93/100 stars

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    Comparison of concentrations of PIP1 α1 and <t>MMP1</t> and mRNA expression levels of COL1A1 , MMP1 , and MMP3 after OLED and LED light irradiation. The 6 J/cm 2 OLED light irradiation significantly induced COL1A1 mRNA expression (A) and PIP1 α1 production (D). The 6 J/cm 2 LED light irradiation significantly induced MMP1 (B) and MMP3 (C) mRNA expression and MMP1 production (E), whereas the 6 J/cm 2 OLED light irradiation significantly reduced MMP3 mRNA expression and MMP1 production. * p <0.05, ** p <0.01, *** p <0.005, independent samples t-test. PIP1 α1, pro-collagen I α1; MMP, matrix metalloproteinase; OLED, organic light-emitting diode; LED, light-emitting diode; HDF, human dermal fibroblast.
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    Image Search Results


    Defect in wound proinflammatory/M1 macrophages and fibroblasts in diabetic mice. A In a mouse model that creates a skin wound in STZ-treated diabetic mice, fibroblasts (DLK1 +), M1 macrophages (F4/80 + CD163-) and M2 macrophages (F4/80 + CD163 +) were isolated from the wound tissue by flow cytometry, shown by representative flow charts. B ELISA for IL1β, IL6, IL10 and VEGF-A in M1 macrophages and for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts. *p < 0.05. NS non-significant. NDW non-diabetic wound. DW Diabetic wound

    Journal: Molecular Biology Reports

    Article Title: Macrophages regulate healing-associated fibroblasts in diabetic wound

    doi: 10.1007/s11033-023-09100-1

    Figure Lengend Snippet: Defect in wound proinflammatory/M1 macrophages and fibroblasts in diabetic mice. A In a mouse model that creates a skin wound in STZ-treated diabetic mice, fibroblasts (DLK1 +), M1 macrophages (F4/80 + CD163-) and M2 macrophages (F4/80 + CD163 +) were isolated from the wound tissue by flow cytometry, shown by representative flow charts. B ELISA for IL1β, IL6, IL10 and VEGF-A in M1 macrophages and for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts. *p < 0.05. NS non-significant. NDW non-diabetic wound. DW Diabetic wound

    Article Snippet: Enzyme-linked immunosorbent assays (ELISAs) were done for IL1β (ab197742; Abcam), tumor necrosis factor alpha (TNFα, ab208348; Abcam), interferon gamma (IFNɣ, ab282874; Abcam), IL6 (Ab100713; Abcam), IL10 (M1000B; R&D Biosystems), CD163 (ab272204; Abcam), transforming growth factor β1 (TGFβ1, ab119557; Abcam), VEGF-A (ab209882; Abcam), fibroblast growth factor 1 (FGF1, ab223587; Abcam), MMP1 (NBP3-06885; Novus Biologicals, Centennial, CO, USA), MMP3 (ab203364; Abcam), MMP11 (NBP3-06935; Novus Biologicals) and CHI3L1 (ab238262; Abcam).

    Techniques: Isolation, Flow Cytometry, Enzyme-linked Immunosorbent Assay

    M1/proinflammatory macrophages regulate the phenotype of fibroblasts. A Fibroblasts isolated from non-diabetic wound were cultured alone, or with isolated M1 macrophages from non-diabetic wound, or with isolated M1 macrophages from diabetic wound. ELISA for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts was performed. B Fibroblasts isolated from diabetic wound were cultured alone, or with isolated M1 macrophages from diabetic wound supplied with/without IL6, or with isolated M1 macrophages from non-diabetic wound. ELISA for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts was performed. *p < 0.05. NS non-significant. NDW non-diabetic wound. DW Diabetic wound

    Journal: Molecular Biology Reports

    Article Title: Macrophages regulate healing-associated fibroblasts in diabetic wound

    doi: 10.1007/s11033-023-09100-1

    Figure Lengend Snippet: M1/proinflammatory macrophages regulate the phenotype of fibroblasts. A Fibroblasts isolated from non-diabetic wound were cultured alone, or with isolated M1 macrophages from non-diabetic wound, or with isolated M1 macrophages from diabetic wound. ELISA for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts was performed. B Fibroblasts isolated from diabetic wound were cultured alone, or with isolated M1 macrophages from diabetic wound supplied with/without IL6, or with isolated M1 macrophages from non-diabetic wound. ELISA for MMP1, MMP3, MMP11, CHI3L1 and VEGF-A in fibroblasts was performed. *p < 0.05. NS non-significant. NDW non-diabetic wound. DW Diabetic wound

    Article Snippet: Enzyme-linked immunosorbent assays (ELISAs) were done for IL1β (ab197742; Abcam), tumor necrosis factor alpha (TNFα, ab208348; Abcam), interferon gamma (IFNɣ, ab282874; Abcam), IL6 (Ab100713; Abcam), IL10 (M1000B; R&D Biosystems), CD163 (ab272204; Abcam), transforming growth factor β1 (TGFβ1, ab119557; Abcam), VEGF-A (ab209882; Abcam), fibroblast growth factor 1 (FGF1, ab223587; Abcam), MMP1 (NBP3-06885; Novus Biologicals, Centennial, CO, USA), MMP3 (ab203364; Abcam), MMP11 (NBP3-06935; Novus Biologicals) and CHI3L1 (ab238262; Abcam).

    Techniques: Isolation, Cell Culture, Enzyme-linked Immunosorbent Assay

    Comparison of concentrations of PIP1 α1 and MMP1 and mRNA expression levels of COL1A1 , MMP1 , and MMP3 after OLED and LED light irradiation. The 6 J/cm 2 OLED light irradiation significantly induced COL1A1 mRNA expression (A) and PIP1 α1 production (D). The 6 J/cm 2 LED light irradiation significantly induced MMP1 (B) and MMP3 (C) mRNA expression and MMP1 production (E), whereas the 6 J/cm 2 OLED light irradiation significantly reduced MMP3 mRNA expression and MMP1 production. * p <0.05, ** p <0.01, *** p <0.005, independent samples t-test. PIP1 α1, pro-collagen I α1; MMP, matrix metalloproteinase; OLED, organic light-emitting diode; LED, light-emitting diode; HDF, human dermal fibroblast.

    Journal: Yonsei Medical Journal

    Article Title: Exploring the Safety and Efficacy of Organic Light-Emitting Diode in Skin Rejuvenation and Wound Healing

    doi: 10.3349/ymj.2023.0125

    Figure Lengend Snippet: Comparison of concentrations of PIP1 α1 and MMP1 and mRNA expression levels of COL1A1 , MMP1 , and MMP3 after OLED and LED light irradiation. The 6 J/cm 2 OLED light irradiation significantly induced COL1A1 mRNA expression (A) and PIP1 α1 production (D). The 6 J/cm 2 LED light irradiation significantly induced MMP1 (B) and MMP3 (C) mRNA expression and MMP1 production (E), whereas the 6 J/cm 2 OLED light irradiation significantly reduced MMP3 mRNA expression and MMP1 production. * p <0.05, ** p <0.01, *** p <0.005, independent samples t-test. PIP1 α1, pro-collagen I α1; MMP, matrix metalloproteinase; OLED, organic light-emitting diode; LED, light-emitting diode; HDF, human dermal fibroblast.

    Article Snippet: After 24 h, to detect pro-collagen type I peptide α1 (PIP1 α1) and MMP1 concentrations, human PIP1 α1 SimpleStep ELISA Kit (ab210966, Abcam, Cambridge, UK) and MMP1 Human ELISA Kit (EHMMP1, Invitrogen, Waltham, MA, USA) were used according to the manufacturers’ instructions.

    Techniques: Comparison, Expressing, Irradiation